magnetic lab-on-a-chip devices
We envisage a miniaturised magnetic lab-on-a-chip device comprising microfluidic channels and magnetic sensors to encode and decode digital magnetic microtags. The microtags serve as encoded carriers for a variety of biochemical compounds, such as oligonucleotides (for DNA/RNA sequencing), antibodies (for immunodiagnostic applications), proteins (for proteomics) or any other compound that can then be used in assays based on molecular recognition processes. The microtags have the capacity of providing a vast number (billions) of unique codes that could be used to identify the biochemical compounds attached to their surface. These carriers flow in microfluidic channels and their magnetically encoded information is read in flow as they pass near the magnetic sensors, enabling high throughput biochemical assays.
The company will offer miniaturised, fully intergrated, portable, low cost and rapid biosensors (magnetic lab-on-a-chip devices) for multiplexed screening of many pathogens or other target biochemical compounds in a single test.
The three unique benefits of the magnetic encoding technology are the abilities to provide
- a vast number of codes
- to write information onto the tags and
- to farbricate fully integrated, miniaturised devices with low cost.
Exploiting the writing ability offers a unique method for synthesising in-situ encoded large chemical libraries utilising combinatorial chemistry methods; this is of particular importance in the drug discovery and development markets. Another unique benefit of our technology is the ability for large volume manufacturing by employing traditional techniques used in the electronics industry of both the integrated lab-on-a-chip device and the magnetic microtags.